Your Location：Home >Products >Analytical Chemistry >616-45-5
pd_meltingpoint:23-25 °C(lit.)
Appearance:clear colorless liquid or low melting solid
Purity:99%
Quality products make an important contribution to long-term revenue and profitability. Hot Sale! High Quality, High Purity 2-Pyrrolidinone 616-45-5 Intermediates Liquid Export with Best Price, Fast Delivery.
2-pyrrolidone widely exists in various physiologically active natural products in nature. It can be purified by vacuum distillation over calcium oxide. 2-Pyrrolidinone is a simple cyclic peptide, whose C double bond O bond structure serves as a model system for the protein backbone amide I band and the N–H bond as the amide A band in the protein and peptide.
carbon monoxide
1-amino-2-propene
2-pyrrolidinon
1,3-diallylurea
| Conditions | Yield |
|---|---|
|
With tributylphosphine; cobalt(II) acetate; In methanol; at 25 ℃; Irradiation;
|
1.8 % Chromat. 20.4 % Chromat. |
carbon monoxide
1-amino-2-propene
2-pyrrolidinon
1,3-diallylurea
N-allyl-3-butenamide
| Conditions | Yield |
|---|---|
|
dicobalt octacarbonyl; In methanol; at 25 ℃; for 18h; Product distribution; Irradiation; other catalyst, other solvents, other gas, other substrates;
|
2.1 % Chromat. 13.0 % Chromat. 3.8 % Chromat. |
|
With hydrogen; dicobalt octacarbonyl; In methanol; at 25 ℃; for 18h; Irradiation;
|
2.6 % Chromat. 13.3 % Chromat. 6.0 % Chromat. |
|
dicobalt octacarbonyl; In benzene; at 25 ℃; for 42h; Irradiation;
|
10.7 % Chromat. 4.8 % Chromat. 17.2 % Chromat. |
The CAS number of 2-Pyrrolidinone is 616-45-5.
More information of 2-Pyrrolidinone 616-45-5 are:
|
CAS Number |
616-45-5 |
|
Density |
1.047 g/cm3 |
|
Melting Point |
23-25 °C(lit.) |
|
Boiling Point |
245 °C at 760 mmHg |
|
Flash Point |
135.5 °C |
|
Vapor Pressure |
0.04 hPa (20 °C) |
|
Refractive Index |
n20/D 1.487(lit.) |
|
HS CODE |
29339980 |
|
PSA |
29.10000 |
|
LogP |
0.22520 |
|
Pka |
16.62±0.20(Predicted) |
Synonyms for 2-Pyrrolidinone 616-45-5:2-Oxopyrrolidine;2-Pyrol;
The chemical formula of 2-Pyrrolidinone is C4H7NO which containing 4 Carbon atoms,7 Hydrogen atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of 2-Pyrrolidinone is 85.1057.
2-Pyrrolidinone is well known to form inter-molecular hydrogen bonding. 2-pyrrolidinone is used as a solvent in the extractive distillation of fuels and solvent extraction processes for separating polar and nonpolar liquids. Many polysubstituted 2-pyrrolidones have been used in the synthesis and production of a variety of drugs and applied for patents. In some studies,2-Pyrrolidinone was used as a model molecule of biological systems.
InChI:InChI=1/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6)
Relevant articles related to 2-Pyrrolidinone:
|
Article |
Source |
| Efficient synthesis of tert-butyl 3-cyano-3-cyclopropyl-2-oxopyrrolidine-4-carboxylates: Highly functionalized 2-pyrrolidinone enabling access to novel macrocyclic Tyk2 inhibitors |
Yusuke Sasaki a, Hidekazu Tokuhara a c, Yusuke Ohba a d, Atsutoshi Okabe a, Masaharu Nakayama a e, Hideyuki Nakagawa a, Robert Skene b, Isaac Hoffman b, Hua Zou b, Masato Yoshida a , Bioorganic & Medicinal Chemistry Letters Volume 30, Issue 5, 1 March 2020, 126963 |
| Anti-paralysis agitans impact of emelista tora britton & rose on 2-pyrrolidinone, 1-(four-(1-pyrrolidinyl)-2-butynyl) brought on anti-paralysis agitans approach |
CP Suryawanshi, JD More, AP Sinhal, SB Patil , International Journal of Academic Research and Development, Volume 8, Issue 1, 2023, Page No. 8-12 |
Jiaozuo Zhongwei Special Products Pharmaceutical Co.,Ltd. is a quality factory of 2-Pyrrolidinone. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 2-Pyrrolidinone 616-45-5.
