Appearance:colourless or light yellow liquid with an amine odour
Purity:99%
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872-50-4 Name |
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Name |
N-METHYL-PYRROLIDONE |
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Synonym |
N-Methyl-2-pyrrolidone;M-PYROL(R);1-Methyl-2-pyrrolidinone( 99.5%, HyDry, Water≤50 ppm (by K.F.));1-Methyl-2-pyrrolidinone( 99.5%, HyDry, with molecular sieves, Water≤50 ppm (by K.F.));N-Methyl-2-pyrrolidone Manufacturer;1-METHYL-2-PYRROLIDONE, REAGENT (ACS)1-METHYL-2-PYRROLIDONE, REAGENT (ACS)1-METHYL-2-PYRROLIDONE, REAGENT (ACS);1-Methyl-2-pyrrolidinone 872-50-4 NMP N-Methyl-2-pyrrolidinone;N-Methyl-2-pyrrolidinone 872-50-4 NMP;1-METHYL-2-PYRROLIDINONE |
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872-50-4 Biological Activity |
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Description |
N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals[1][2]. |
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Related Catalog |
Research Areas >> Others Signaling Pathways >> Others >> Others |
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References |
[1]. Jing Wang, et al. Nitrate stimulation of N-Methylpyrrolidone biodegradation by Paracoccus pantotrophus: Metabolite mechanism and Genomic characterization. Bioresour Technol. 2019 Dec;294:122185. [2]. Claudia Julieta Solís-González, et al. Novel Metabolic Pathway for N-Methylpyrrolidone Degradation in Alicycliphilus sp. Strain BQ1. Appl Environ Microbiol. 2017 Dec 15;84(1):e02136-17. |
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872-50-4 Chemical & Physical Properties |
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Melting point |
−24 °C(lit.) |
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Boiling point |
202.0±0.0 °C at 760 mmHg |
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Density |
1.0±0.1 g/cm3 |
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Molecular Formula |
C5H9NO |
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Molecular Weight |
99.131 |
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Flash Point |
86.1±0.0 °C |
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PSA |
20.31000 |
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LogP |
-0.40 |
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Exact Mass |
99.068413 |
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Vapour density |
3.4 (vs air) |
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Vapour Pressure |
0.3±0.4 mmHg at 25°C |
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Index of Refraction |
1.470 |
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Stability |
Stable, but decomposes upon exposure to light. Combustible. Incompatible with strong oxidizing agents, strong acids, reducing agents, bases. |
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Water Solubility |
>=10 g/100 mL at 20 ºC |
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872-50-4 Description |
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N-Methyl-2-Pyrrolidone (NMP) is a powerful, aprotic solvent with high solvency, and low volatility. This colorless, high boiling, high flash point and low vapor pressure liquid carries a mild amine-like odor. NMP has high chemical and thermal stability and is completely miscible with water at all temperatures. NMP can serve as a co-solvent with water, alcohols, glycol ethers, ketones, and aromatic/chlorinated hydrocarbons. NMP is both recyclable by distillation and readily biodegradable. NMP is not found on the Hazardous Air Pollutants (HAPs) list of the 1990 Clean Air Act Amendments. |
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872-50-4 Uses |
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872-50-4 Production Methods |
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N-Methyl-2-pyrrolidone is manufactured by the reaction of buytrolactone with methylamine (Hawley 1977). Other processes include preparation by hydrogenation of solutions of maleic or succinic acids with methylamine (Hort and Anderson 1982). Manufacturers of this chemical include Lachat Chemical, Inc, Mequon, Wisconsin and GAF Corporation, Covert City, California. |
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872-50-4 Safety Profile |
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Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by skin contact. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Combustible when exposed to heat, open flame, or powerful oxidizers. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx. |
