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pd_meltingpoint:13-14 °C
Appearance:liquid
Purity:99%
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N-vinylpyrrolidone (NVP) is one of such monomers known for its biocompatibility which has received lots of attention due to its low cytotoxicity and high hydrophilicity.
1-(2-hydroxyethyl)-2-pyrrolidinone
1-ethenyl-2-pyrrolidinone
Conditions | Yield |
---|---|
With Na/SiO2; ammonia; at 350 ℃; for 10h; under 750.075 Torr; Reagent/catalyst; Temperature; Catalytic behavior;
|
90% |
Ca/Zn oxide; at 348 ℃; for 1h;
|
82% |
Ca/Zn oxide; at 331 - 359 ℃; for 1h;
|
67.5% |
zinc-magnesium mixed oxide; at 356 - 360 ℃; for 2 - 4h;
|
66.7% |
Ca/Zn oxide calcined in air to 500 C; at 366 ℃; for 1h;
|
44% |
magnesium oxide; at 368 ℃; for 1h;
|
26.6% |
Ca/Zn oxide calcined in air to 700 C; at 359 ℃; for 1h;
|
11.5% |
calcium carbonate; at 377 ℃; for 1h;
|
2.7% |
With aluminum oxide; at 300 - 340 ℃; under 56 Torr; Beim Leiten des Dampfes von Edukt ueber Reagens;
|
|
Multi-step reaction with 2 steps
1: benzene; thionyl chloride
2: benzene; sodium amide
With thionyl chloride; sodium amide; benzene;
|
|
Product distribution / selectivity;
|
|
With Cs2O#SiO2; at 500 ℃; for 2h;
|
|
Gas phase;
|
|
With Cs1Si10 catalyst; for 1h; under 760.051 Torr; Inert atmosphere; Sealed tube;
|
87 %Chromat. |
With sodium oxide-silicon dioxide; at 350 ℃; Temperature; Catalytic behavior; Flow reactor; Green chemistry;
|
2-pyrrolidinon
[1,3]-dioxolan-2-one
1-ethenyl-2-pyrrolidinone
Conditions | Yield |
---|---|
With TEMPOL; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 5,5-dimethyl-1,3-cyclohexadiene; at 100 - 120 ℃; for 3.5h; Dean-Stark;
|
82.13% |
The CAS number of N-Vinyl-2-pyrrolidone is 88-12-0.
More information of N-Vinyl-2-pyrrolidone 88-12-0 are:
CAS Number |
88-12-0 |
Density |
1.144 g/cm3 |
Melting Point |
13-14 °C |
Boiling Point |
217.6 °C at 760 mmHg |
Flash Point |
93.9 °C |
Vapor Pressure |
0.1 mm Hg ( 24 °C) |
Refractive Index |
n20/D 1.512(lit.) |
HS CODE |
29337900 |
ICSC Number | 1478 |
PSA |
20.31000 |
LogP |
0.69020 |
Pka |
-0.34±0.20(Predicted) |
Synonyms for N-Vinyl-2-pyrrolidone 88-12-0:2-Pyrrolidinone,1-vinyl- (7CI,8CI);1-Ethenyl-2-pyrrolidinone;1-Vinyl-2-pyrrolidinone;1-Vinyl-2-pyrrolidone;Aronix M 150;N-V 2RC;N-VP;N-Vinyl-2-pyrrolidinone;N-Vinylpyrrolin-2-one;NSC 10222;NSC 683040;NVP 300;V-Pyrol;V-Pyrol RC;Vinylbutyrolactam;2-Pyrrolidinone,1-ethenyl-;
The chemical formula of N-Vinyl-2-pyrrolidone is C6H9NO which containing 6 Carbon atoms,9 Hydrogen atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of N-Vinyl-2-pyrrolidone is 111.144.
N-vinyl-2-pyrrolidone (NVP) is widely used in biomedical field, food packaging and surface coatings, etc. The polymers synthesized using NVP as monomer/polymer find applications in plasma substitutes, soluble drug carriers, and UV-curable bioadhesives. Poly(N-vinylpyrrolidone) is one of the most often investigated classes of materials for use in medicine and in other applications interfacing with biological systems.
Isomeric SMILES: C=CN1CCCC1=O
InChIKey: WHNWPMSKXPGLAX-UHFFFAOYSA-N
InChI: InChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
Relevant articles related to N-Vinyl-2-pyrrolidone:
Article |
Source |
《N-vinylpyrrolidone antimicrobial polymers: Current trends and emerging perspectives》 European Polymer Journal Volume 180, 5 November 2022, 111590 |
The polymerization of NVP can be done by various methods and is readily polymerized to produce a polymer, poly(N-vinylpyrrolidone) (PVP), which is soluble in many organic solvents also water. In summary, this review highlights the use of N-vinylpyrrolidone in the synthesis of antimicrobial polymers due to their wide range of… |
《A self-healing, stretchable, and conductive Poly (N-vinylpyrrolidone)/gallic acid composite hydrogel formed via hydrogen bonding for wearable electronic sensors》 Composites Science and Technology Volume 198, 29 September 2020, 108294 |
A self-healable, injectable, stretchable, self-adhesive, biocompatible, and conductive poly(N-vinylpyrrolidone)/gallic acid (PVP/GA) composite hydrogel was fabricated via hydrogen bonding between the tertiary amide groups in PVP and hydroxyl groups in GA. It is envisioned that multifunctional PVP/GA composite hydrogels can be applied to the electronic skins, wearable biosensors, and body movements monitoring equipment. |
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